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Table 3 Nailfold videocapillaroscopy characteristics and comparisons between groups of patients depending on pulmonary involvement

From: Quantitative videocapillaroscopy correlates with functional respiratory parameters: a clue for vasculopathy as a pathogenic mechanism for lung injury in systemic sclerosis

 

ILD comparisons

p value

PAH comparisons

p value

ILD (n = 58)

No ILD (n = 76)

PAH (n = 11)

No PAH (n = 123)

Quantitative NVC features

 Capillary density (n) ª

4.86 (4.14–5.80)

5.88 (4.74–6.85)

0.005*

5.47 (5.00–5.83)

5.42 (4.31–6.74)

0.997

 Enlarged capillaries (n) ª

0.84 (0.31–1.53)

0.85 (0.39–1.58)

0.738

0.56 (0.25–0.93)

0.91 (0.40–1.61)

0.128

 Giant capillaries (n) ª

0.26 (0.00–0.64)

0.30 (0.04–1.07)

0.362

0.06 (0.00–0.40)

0.29 (0.03–1.02)

0.167

 Microhaemorrhages (n) ª

0.12 (0.00–0.38)

0.13 (0.00–0.42)

0.735

0.06 (0.00–0.22)

0.14 (0.00–0.40)

0.101

 Tortuous capillaries (n) ª

0.45 (0.19–1.31)

0.72 (0.28–1.49)

0.216

0.63 (0.25–1.71)

0.59 (0.23–1.43)

0.773

 Neoangiogenesis (n) ª

0.56 (0.23–1.28)

0.31 (0.12–0.62)

0.005*

0.70 (0.47–1.80)

0.33 (0.12–0.78)

0.007*

Qualitative NVC features

 Cutolo’s pattern, early/active/late

8 (13.8)/23 (39.7)/23 (39.7)

15 (19.7)/36 (47.4)/14 (18.4)

0.366/0.373/0.006*

1 (9.1)/4 (36.4)/6 (54.5)

21 (17.9)/52 (44.4)/29 (24.8)

0.688/0.755/0.069

  1. Data presented as median (interquartile range) for continuous variables and as number (%) for categorical variables
  2. ILD interstitial lung disease, PAH pulmonary arterial hypertension, NVC nailfold videocapillaroscopy
  3. ªAdjusted by each millimetre of the nailfold
  4. *Statistically significant comparison after Bonferroni correction (p < 0.008)