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Table 3 Nailfold videocapillaroscopy characteristics and comparisons between groups of patients depending on pulmonary involvement

From: Quantitative videocapillaroscopy correlates with functional respiratory parameters: a clue for vasculopathy as a pathogenic mechanism for lung injury in systemic sclerosis

  ILD comparisons p value PAH comparisons p value
ILD (n = 58) No ILD (n = 76) PAH (n = 11) No PAH (n = 123)
Quantitative NVC features
 Capillary density (n) ª 4.86 (4.14–5.80) 5.88 (4.74–6.85) 0.005* 5.47 (5.00–5.83) 5.42 (4.31–6.74) 0.997
 Enlarged capillaries (n) ª 0.84 (0.31–1.53) 0.85 (0.39–1.58) 0.738 0.56 (0.25–0.93) 0.91 (0.40–1.61) 0.128
 Giant capillaries (n) ª 0.26 (0.00–0.64) 0.30 (0.04–1.07) 0.362 0.06 (0.00–0.40) 0.29 (0.03–1.02) 0.167
 Microhaemorrhages (n) ª 0.12 (0.00–0.38) 0.13 (0.00–0.42) 0.735 0.06 (0.00–0.22) 0.14 (0.00–0.40) 0.101
 Tortuous capillaries (n) ª 0.45 (0.19–1.31) 0.72 (0.28–1.49) 0.216 0.63 (0.25–1.71) 0.59 (0.23–1.43) 0.773
 Neoangiogenesis (n) ª 0.56 (0.23–1.28) 0.31 (0.12–0.62) 0.005* 0.70 (0.47–1.80) 0.33 (0.12–0.78) 0.007*
Qualitative NVC features
 Cutolo’s pattern, early/active/late 8 (13.8)/23 (39.7)/23 (39.7) 15 (19.7)/36 (47.4)/14 (18.4) 0.366/0.373/0.006* 1 (9.1)/4 (36.4)/6 (54.5) 21 (17.9)/52 (44.4)/29 (24.8) 0.688/0.755/0.069
  1. Data presented as median (interquartile range) for continuous variables and as number (%) for categorical variables
  2. ILD interstitial lung disease, PAH pulmonary arterial hypertension, NVC nailfold videocapillaroscopy
  3. ªAdjusted by each millimetre of the nailfold
  4. *Statistically significant comparison after Bonferroni correction (p < 0.008)