Quantitative videocapillaroscopy correlates with functional respiratory parameters: a clue for vasculopathy as a pathogenic mechanism for lung injury in systemic sclerosis

Table 6 Multiple regression analysis according to quantitative nailfold videocapillaroscopy

	B	95% CI	p value
FVC as dependent variable
Male gender	−11.0	−19.2 to −2.9	0.008
Interstitial findings on HRCT	−14.8	−21.1 to −8.4	< 0.001
ACA positivity	7.2	0.1 to 14.3	0.045
Neoangiogenesis/mm	−7.3	−11.0 to −3.6	< 0.001
DLCO as dependent variable
Digital ulcers	−6.7	−13.6 to 0.1	0.056
Interstitial findings on HRCT	−9.4	−16.4 to −2.5	0.008
FVC	0.5	0.3 to 0.7	<0.001
PAH confirmed by RHC	−14.3	−26.9 to −1.6	0.027
TRV ≥ 2.9 m/s or other echo PH signs	−16.4	− 28.3 to −4.6	0.007
Enlarged capillaries	7.8	1.1 to 14.4	0.021
Giant capillaries	−11.8	−21.4 to −2.2	0.016

Only variables with statistical significance or tendency to be significant are presented
B regression coefficient, CI confidence interval, FVC forced vital capacity, HRCT high resolution computed tomography, ACA anticentromere antibodies, DLCO diffusion capacity of the lung for carbon monoxide, PAH pulmonary arterial hypertension, RHC right heart catheterization, TRV tricuspid regurgitation velocity, PH pulmonary hypertension

ISSN: 1478-6362