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Table 6 Multiple regression analysis according to quantitative nailfold videocapillaroscopy

From: Quantitative videocapillaroscopy correlates with functional respiratory parameters: a clue for vasculopathy as a pathogenic mechanism for lung injury in systemic sclerosis

  B 95% CI p value
FVC as dependent variable
 Male gender −11.0 −19.2 to −2.9 0.008
 Interstitial findings on HRCT −14.8 −21.1 to −8.4 < 0.001
 ACA positivity 7.2 0.1 to 14.3 0.045
 Neoangiogenesis/mm −7.3 −11.0 to −3.6 < 0.001
DLCO as dependent variable
 Digital ulcers −6.7 −13.6 to 0.1 0.056
 Interstitial findings on HRCT −9.4 −16.4 to −2.5 0.008
 FVC 0.5 0.3 to 0.7 <0.001
 PAH confirmed by RHC −14.3 −26.9 to −1.6 0.027
 TRV ≥ 2.9 m/s or other echo PH signs −16.4 − 28.3 to −4.6 0.007
 Enlarged capillaries 7.8 1.1 to 14.4 0.021
 Giant capillaries −11.8 −21.4 to −2.2 0.016
  1. Only variables with statistical significance or tendency to be significant are presented
  2. B regression coefficient, CI confidence interval, FVC forced vital capacity, HRCT high resolution computed tomography, ACA anticentromere antibodies, DLCO diffusion capacity of the lung for carbon monoxide, PAH pulmonary arterial hypertension, RHC right heart catheterization, TRV tricuspid regurgitation velocity, PH pulmonary hypertension