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Table 7 Multiple regression analysis according to Cutolo’s patterns

From: Quantitative videocapillaroscopy correlates with functional respiratory parameters: a clue for vasculopathy as a pathogenic mechanism for lung injury in systemic sclerosis

  B 95% CI p value
FVC as dependent variable
 Male gender −12.3 −21.0 to −3.5 0.006
 Interstitial findings on HRCT −13.5 −20.2 to −6.7 < 0.001
 ACA positivity 8.6 −0.1 to 17.4 0.051
 Cutolo’s late pattern −14.3 −26.1 to −2.5 0.018
DLCO as dependent variable
 Digital ulcers −8.3 −14.8 to −1.8 0.013
 Interstitial findings on HRCT −9.8 −16.8 to −2.8 0.006
 FVC 0.5 0.3 to 0.7 < 0.001
 PH confirmed by RHC −14.1 −26.8 to −1.5 0.028
 TRV ≥ 2.9 m/s or other echo PH signs − 14.9 −26.8 to −3.0 0.014
  1. Only variables with statistical significance or tendency to be significant are presented
  2. B regression coefficient, CI confidence interval, FVC forced vital capacity, HRCT high resolution computed tomography, ACA anticentromere antibodies, DLCO diffusion capacity of the lung for carbon monoxide, PAH pulmonary arterial hypertension, PH pulmonary hypertension, RHC right heart catheterization, TRV tricuspid regurgitation velocity