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Table 7 Multiple regression analysis according to Cutolo’s patterns

From: Quantitative videocapillaroscopy correlates with functional respiratory parameters: a clue for vasculopathy as a pathogenic mechanism for lung injury in systemic sclerosis

 

B

95% CI

p value

FVC as dependent variable

 Male gender

−12.3

−21.0 to −3.5

0.006

 Interstitial findings on HRCT

−13.5

−20.2 to −6.7

< 0.001

 ACA positivity

8.6

−0.1 to 17.4

0.051

 Cutolo’s late pattern

−14.3

−26.1 to −2.5

0.018

DLCO as dependent variable

 Digital ulcers

−8.3

−14.8 to −1.8

0.013

 Interstitial findings on HRCT

−9.8

−16.8 to −2.8

0.006

 FVC

0.5

0.3 to 0.7

< 0.001

 PH confirmed by RHC

−14.1

−26.8 to −1.5

0.028

 TRV ≥ 2.9 m/s or other echo PH signs

− 14.9

−26.8 to −3.0

0.014

  1. Only variables with statistical significance or tendency to be significant are presented
  2. B regression coefficient, CI confidence interval, FVC forced vital capacity, HRCT high resolution computed tomography, ACA anticentromere antibodies, DLCO diffusion capacity of the lung for carbon monoxide, PAH pulmonary arterial hypertension, PH pulmonary hypertension, RHC right heart catheterization, TRV tricuspid regurgitation velocity