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Table 4 Correlations between the immunoglobulin G4-related disease responder index score or the number of organ involvements and the biomarkers

From: Association of serum levels of fibrosis-related biomarkers with disease activity in patients with IgG4-related disease

  IgG4-RD responder index Number of organ involvements
rs P value rs P value
GDF-15 0.11 0.35 0.07 0.54
CCL2 0.07 0.56 0.03 0.81
TIMP-1 0.11 0.36 0.10 0.42
HA 0.17 0.16 0.17 0.15
PIIINP −0.19 0.10 −0.17 0.16
ELF score −0.07 0.58 −0.04 0.73
IgG 0.49 <0.0001 0.43 0.0002
IgG4 0.64 <0.0001 0.61 <0.0001
CH50 −0.21 0.10 −0.24 0.063
C3 −0.27 0.029 −0.28 0.022
C4 −0.33 0.0066 −0.35 0.0043
sIL-2R 0.52 <0.0001 0.51 <0.0001
  1. The results were obtained using Spearman’s correlation coefficient. Abbreviations: CCL2 CC chemokine ligand 2, ELF enhanced liver fibrosis, GDF-15 growth differentiation factor 15, HA hyaluronic acid, IgG4-RD immunoglobulin G4-related disease, PIIINP amino-terminal propeptide of type III procollagen, sIL-2R soluble interleukin-2 receptor, TIMP-1 tissue inhibitor of metalloproteinases 1