Table 2 The incidence of giant cell arteritis (GCA) in Bergen health area 1972–2012
a Mean annual cumulative incidence | ||||||
All time | 1972–1992 | 1993–2012 | ||||
Cumulative incidence | 95% CI | Cumulative incidence | 95% CI | Cumulative incidence | 95% CI | |
All patients | 16.7 | (15.5, 18.0) | 11.2 | (9.8, 12.7) | 22.5 | (20.5, 24.7) |
Sex | ||||||
Female | 22.0 | (20.6, 23.5) | 13.3 | (11.8, 14.9) | 31.2 | (28.8, 33.7) |
Male | 10.5 | (9.5, 11.5) | 8.6 | (7.4, 9.9) | 12.4 | (10.9, 14.0) |
Age, years | ||||||
< 60 | 2.8 | (2.3, 3.3) | 1.5 | (1.0, 2.1) | 4.1 | (3.3, 5.0) |
60–69 | 15.5 | (14.4, 16.8) | 10.9 | (9.6, 12.4) | 20.3 | (18.4, 22.4) |
70–79 | 34.5 | (32.8, 36.4) | 23.4 | (21.4, 25.6) | 46.2 | (43.3, 49.2) |
80+ | 26.8 | (25.3, 28.4) | 14.3 | (12.8, 16.0) | 39.9 | (37.2, 42.7) |
ESR, mm/hr | ||||||
ESR < 85 | 8.2 | (7.3, 9.1) | 4.5 | (3.7, 5.5) | 12.0 | (10.6, 13.6) |
ESR > 85 | 8.4 | (7.6, 9.3) | 6.6 | (5.5, 7.7) | 10.4 | (9.0, 11.8) |
b Relative risk (RR) according to time, sex, age and ESR | ||||||
1972–1992 | 1993–2012 | |||||
RR | 95% CI | p-value | RR | 95% CI | p-value | |
Unadjusted | ||||||
Time (years) | 1.1 | (1.1, 1.1) | < 0.001 | 1.0 | (1.0, 1.0) | 0.543 |
Sex | ||||||
Time (years) | 1.1 | (1.1, 1.1) | < 0.001 | 1.0 | (1.0, 1.0) | 0.462 |
Sex (Male vs. Female) | 0.6 | (0.5, 0.8) | < 0.001 | 0.4 | (0.3, 0.5) | < 0.001 |
Age | ||||||
Time (years) | 1.1 | (1.1, 1.1) | < 0.001 | 1.0 | (1.0, 1.0) | 0.135 |
60–69 vs. < 60 | 7.2 | (5.1, 10.6) | < 0.001 | 5.0 | (3.9, 6.4) | < 0.001 |
70–79 vs. < 60 | 15.4 | (11.0, 22.5) | < 0.001 | 11.3 | (9.1, 14.3) | < 0.001 |
80+ vs. < 60 | 9.5 | (6.7, 13.9) | < 0.001 | 9.8 | (7.8, 12.4) | < 0.001 |
ESR | ||||||
Time (years) | 1.1 | (1.1, 1.1) | < 0.001 | 1.0 | (1.0, 1.0) | 0.632 |
ESR (>median vs. <median) | 1.4 | (1.1, 1.9) | 0.006 | 0.9 | (0.7, 1.0) | 0.116 |