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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis

Fig. 5

Potassium channel blockers alter serum cytokines in collagen-induced arthritis (CIA). a–i Serum concentrations of tumor necrosis factor (TNF)-α, interleukin (IL)-4, IL-12, IL-17A, monocyte chemoattractant protein (MCP)-1, IL-2, IL-1β, IL-6, and IL-10 from healthy rats or rats with CIA treated with vehicle, ShK-186, iberiotoxin (IbTX), or both ShK-186 and IbTX every other day for 14 days after disease onset. Data are presented as mean ± SEM (n = 5 or 6 rats per group). *p < 0.05

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Arthritis Research & Therapy

ISSN: 1478-6362

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