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Table 2 Multivariate regression analysis for hip OA at 2-years and/or 5-year follow up according to the ACR classification criteria (n = 198, 80 cases, a priori risk = 0.40)

From: Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort

Baseline characteristics Analysis per category OR (95% CI) Multivariate analysis OR(95% CI) PPV NPV LR+ LR-
Demographics
 Age (<= 50vs. > 50 years) 0.53(0.28–1.01) 0.90(0.41–1.99) 0.36 0.48 0.84 1.6
Complaints and symptoms
 Pain last week, NRS 1.15(0.99–1.33) 1.04(0.87–1.26) na na na na
 Morning stiffness hip (yes = 1/no = 0) 2.60 (1.14–3.71) 2.39 (1.14–4.98) 0.51 0.66 1.56 0.75
Comorbidities and interventions
 Knee pain (yes = 1/no = 0) 0.63 (0.33–1.20) 0.71 (0.32–1.55) 0.37 0.51 0.89 1.42
 Painkillers (yes = 1/no = 0) 2.01 (1.12–3.59) 1.60 (0.75–3.41) 0.5 0.67 1.47 0.73
Physical examination
 Painful hip internal rotation (yes = 1/no = 0) 2.59 (1.43–4.67) 2.53 (1.23–5.19) 0.53 0.69 1.71 0.66
 Hip flexion ROM (0 = > 115° vs. 1 = <= 115°) 2.00 (1.12–3.67) 2.33 (1.17–4.64) 0.5 0.67 1.47 0.73
Diagnostic tests
 ESR < 20 mm/h 3.54 (1.30–7.13) 2.94 (1.13–7.61) 0.46 0.77 1.22 0.4
  1. Bold values indicate significant values (p < 0.05) in the final model
  2. ACR American College of Rheumatology, OR odds ratio, PPV positive predictive value, NPV negative predictive value, NRS numeric rating scale, ROM range of motion, LR+ positive likelihood ratio, LR- negative likelihood ratio, na not applicable (continuous variable), ESR erythrocyte sedimentation rate