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Table 3 Multivariate regression analysis for knee OA at 2-year and/or 5-year follow up according to the ACR classification criteria (n = 64, 35 cases, a priori risk = 0.55)

From: Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort

Baseline characteristics

Analysis per category OR (95% CI)

Multivariate analysis OR (95% CI)

PPV

NPV

LR+

LR-

Demographics

 Age (<=50 vs. > 50 years)

0.37 (0.13–1.36)

0.42 (0.14–1.06)

0.39

0.37

0.53

1.44

Complaints and symptoms

 Morning stiffness knee (yes = 1/no = 0)

6.79 (0.65–51.23)

6.08 (0.53–69.93)

0.86

0.49

4.97

0.08

Physical examination

 Joint line tenderness

1.05 (0.21–5.14)

1.92 (0.34–10.79)

0.73

0.5

2.2

0.8

Diagnostic tests

 ESR < 20 mm/h

0.94 (0.87–1.02)

0.94 (0.85–1.03)

na

na

na

na

  1. OR odds ratio, PPV positive predictive value, NPV negative predictive value, NRS numeric rating scale, ESR erythrocyte sedimentation rate, LR+ positive likelihood ratio, LR- negative likelihood ratio, na not applicable (continuous variable)
  2. p < 0.05
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Arthritis Research & Therapy

ISSN: 1478-6362

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