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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: Impairment of glyoxalase-1, an advanced glycation end-product detoxifying enzyme, induced by inflammation in age-related osteoarthritis

Fig. 7

Involvement of nuclear factor-erythroid 2-related factor-2 (Nrf-2) in the downregulation of glyoxalase-1 (Glo-1) induced by interleukin-1β (IL-1β; 5 ng/mL). Cells were obtained from wild-type or Nrf-2−/− mice. Quantitative RT-PCR analysis of mRNA levels of Glo-1 relative to hypoxanthine guanine phosphoribosyltransferase (HPRT), n = 3 for wild-type, n = 4 for Nrf-2−/−. Data are presented as median and interquartile. KO knockout

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Arthritis Research & Therapy

ISSN: 1478-6362

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