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Table 2 Correlation between ultrasonography and synovial fluid cytokines in patients with RA

From: Significant association between joint ultrasonographic parameters and synovial inflammatory factors in rheumatoid arthritis

 

Untreated (n = 19)

Treated (n = 25)

Hypertrophy

Vascularity

Echogenicity

Hypertrophy

Vascularity

Echogenicity

IL-6

0.75*

0.80*

0.01

0.38

0.65*

−0.46*

VEGF

0.21

0.68*

0.15

0.28

0.43*

−0.55*

IL-8

0.30

0.41

− 0.15

0.13

0.33

−0.17

TNF-α

0.29

0.37

0.01

0.09

0.11

0.08

IL-1β

0.49*

0.65*

0.05

0.27

0.27

−0.03

IL-10

0.68*

0.68*

0.16

0.32

0.39

−0.35

IL-17A

0.63*

0.47*

0.20

0.14

0.31

−0.17

Fractalkine

0.36

0.46*

0.02

0.24

0.21

−0.12

Granzyme B

0.60*

0.63*

−0.02

0.15

0.17

0.27

  1. Values are Spearman’s rho; *significant correlation (p < 0.05)
  2. Hypertrophy quantitative grayscale area (×103 pixel counts), vascularity quantitative power Doppler area (×103 pixel counts), echogenicity quantitative gray value of grayscale area, IL interleukin, VEGF vascular endothelial growth factor, TNF tumor necrosis factor