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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: IgG4:IgG RNA ratio differentiates active disease from remission in granulomatosis with polyangiitis: a new disease activity marker? A cross-sectional and longitudinal study

Fig. 4

Correlation between qPCR test and Birmingham Vasculitis Activity Score (BVAS). a Correlation between BVAS (x-axis) and the percentage of immunoglobulin G subtype 4 (IgG4) from total IgG RNA molecules (y-axis) in all individuals. The blue parts of the graph depict the areas where patients are expected in case of remission/low disease activity (BVAS < 3 and qPCR < 11.2%, lower left quadrant) and activity (BVAS ≥ 3 and qPCR ≥ 11.2%, upper right quadrant). b Correlation between ∆BVAS and ∆qPCR in the ten longitudinal cohort subjects

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