Skip to main content

Table 1 Patient characteristics and disease activity parameters in total granulomatosis with polyangiitis cohort, active patients as determined by Birmingham Vasculitis Activity Score ≥ 3, and patients in remission/low disease activity as determined by Birmingham Vasculitis Activity Score < 3

From: IgG4:IgG RNA ratio differentiates active disease from remission in granulomatosis with polyangiitis: a new disease activity marker? A cross-sectional and longitudinal study

  Overall Active Remission/LDA p Value
Patient characteristics
 No. of patients 35 15 20 N/A
 Sex (males/females) 16/19 7/8 9/11 ns
 Age, years (mean + range) 54 (20–78) 59 (20–73) 50 (28–78) ns
 Years since diagnosis (median + IQR) 5 (1–12) 3 (1–12) 7 (1.3–12.8) ns
Disease activity parameters
 BVAS (median + IQR)   8 (5–10) 0 (0–0) < 0.0001
 Physician VAS (median + IQR)   6 (2–8) 0 (0–0.5) < 0.0001
 CRP (mg/L) (median + IQR)   30.9 (6.5–70.7) 2.5 (1.9–8.7) < 0.01
 ESR (mm/h) (median + IQR)   20.5 (5–38) 5 (5–10) < 0.05
 Prednisolone (mg/d) (median + IQR)   7.5 (5–15) 5.8 (0.3–13.8) ns
 PR3-ANCA (kIU/L) (median + IQR)   124.6 (4.2–409) 16 (2.4–80.8) ns
  1. Abbreviations: ANCA Antineutrophil cytoplasmic antibodies, BVAS Birmingham Vasculitis Activity Score, CRP C-reactive protein, ESR Erythrocyte sedimentation rate, LDA Low disease activity, ns Not significant, PR3 Proteinase 3, VAS Visual analogue scale