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Table 2 Association between MRI sacroiliac inflammation and IL23R and ERAP1 SNP and haplotype genotypes

From: Association between IL23R and ERAP1 polymorphisms and sacroiliac or spinal MRI inflammation in spondyloarthritis: DESIR cohort data

  Number of patients (%) p value comparison of distribution p value for Cochran-Armitage trend test
ERAP1
 rs27044
  GG 21 (39.62) 0.5 0.25
  CG 98 (35.25)   
  CC 94 (32.19)   
 rs30187
  TT 36 (37.5) 0.07 0.04
  CT 113 (37.5)   
  CC 65 (28.4)   
 rs27434
  GG 105 (30.3) 0.04 0.01
  AG 92 (38.1)   
  AA 16 (47.1)   
 Haplotype CCT*
  0 copy 4 (14.8) 0.02 0.007
  1 copy 55 (29.4)   
  2 copies 153 (37.2)   
IL23R
 rs1004819
  TT 30 (42.3) 0.001 0.0005
  CT 109 (40.5)   
  CC 75 (26.5)   
 rs10489629
  GG 35 (29.2) 0.3 0.1
  AG 101 (33.8)   
  AA 77 (38.1)   
 rs1343151
  TT 24 (30.4) 0.02 0.02
  CT 82 (29.5)   
  CC 108 (40.3)   
 rs11209032
  GG 74 (35.4) 0.03 0.01
  AG 109 (47.3)   
  AA 26 (41.3)   
 Haplotype GA*
  0 copy 80 (28.9) 0.02 0.0054
  1 copy 103 (37.6)   
  2 copies 30 (44.1)   
  1. *: Haplotype CCT: rs17482078, rs10050860, rs2287987; haplotype GA: rs2201841, rs10889677