Table 2 Association between MRI sacroiliac inflammation and IL23R and ERAP1 SNP and haplotype genotypes
Number of patients (%) | p value comparison of distribution | p value for Cochran-Armitage trend test | |
|---|---|---|---|
ERAP1 | |||
rs27044 | |||
GG | 21 (39.62) | 0.5 | 0.25 |
CG | 98 (35.25) | ||
CC | 94 (32.19) | ||
rs30187 | |||
TT | 36 (37.5) | 0.07 | 0.04 |
CT | 113 (37.5) | ||
CC | 65 (28.4) | ||
rs27434 | |||
GG | 105 (30.3) | 0.04 | 0.01 |
AG | 92 (38.1) | ||
AA | 16 (47.1) | ||
Haplotype CCT* | |||
0 copy | 4 (14.8) | 0.02 | 0.007 |
1 copy | 55 (29.4) | ||
2 copies | 153 (37.2) | ||
IL23R | |||
rs1004819 | |||
TT | 30 (42.3) | 0.001 | 0.0005 |
CT | 109 (40.5) | ||
CC | 75 (26.5) | ||
rs10489629 | |||
GG | 35 (29.2) | 0.3 | 0.1 |
AG | 101 (33.8) | ||
AA | 77 (38.1) | ||
rs1343151 | |||
TT | 24 (30.4) | 0.02 | 0.02 |
CT | 82 (29.5) | ||
CC | 108 (40.3) | ||
rs11209032 | |||
GG | 74 (35.4) | 0.03 | 0.01 |
AG | 109 (47.3) | ||
AA | 26 (41.3) | ||
Haplotype GA* | |||
0 copy | 80 (28.9) | 0.02 | 0.0054 |
1 copy | 103 (37.6) | ||
2 copies | 30 (44.1) | ||