Association between IL23R and ERAP1 polymorphisms and sacroiliac or spinal MRI inflammation in spondyloarthritis: DESIR cohort data

Table 3 Association between rs1004819 located on IL23R genotypes and clinical and biological activity, SPARCC score and MRI-detected spinal inflammation

rs1004819, by genotype	TT	CT	CC	Comparison* across genotypes p value
BASDAI, med (IQR)	38 (24–53)	48 (30–62)	48 (28–62)	0.1
ASDAS-CRP med (IQR)	2.5 (1.7–3.3)	2.8 (2.0–3.4)	2.7 (2.0–3.4)	0.5
CRP, med (IQR)	3.6 (2.0–8.0)	3.5 (2.0–7.0)	3 (2.0–8.8)	0.3
SPARCC, med (IQR)	0.0 (0.0–8.0)	0.5 (0.0–5.5)	0.0 (0.0–2.0)	0.0008
Patients with MRI spinal inflammation, n (%)	11 (15.9)	20 (7.8)	18 (6.6)	0.03
Berlin score, med (IQR)	0 (0–1)	0 (0–0)	0 (0–0)	0.09

*p value with a Cochrane-Armitage trend test in case of dichotomous variable and Cuzick trend tests in case of continuous variable
BASDAI Bath Ankylosing Spondylitis Disease Activity Index, ASDAS-CRP Ankylosing Spondylitis Disease Activity Score with CRP, mSASSS Modified Stoke Ankylosing Spondylitis Spine Score, SPARCC Spondyloarthritis Research Consortium of Canada scoring system (sacroiliac joints MRI scoring system), Berlin score spinal MRI scoring system

ISSN: 1478-6362