Table 1 Baseline demographics for all participants
Variable | Category | Overall | Diffuse SSc | Limited SSc | p value | |||
|---|---|---|---|---|---|---|---|---|
N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | |||
Age, mean (SD) (years) | 300 | 50.3 (11.3) | 177 | 49.3 (11.5) | 123 | 51.6 (10.9) | 0.08 | |
Disease duration (years) | 297 | 2.9 (2.0) | 176 | 2.9 (1.9) | 121 | 2.9 (2.1) | 0.79 | |
Gender, N (%) | Male | 84 (28%) | 54 (31%) | 30 (24%) | 0.25 | |||
Female | 216 (72%) | 123 (69%) | 93 (76%) | |||||
SSc type, N (%) | Diffuse | 177 (59%) | 177 (100%) | 0 (0%) | ||||
Limited | 123 (41%) | 0 (0%) | 123 (100%) | |||||
Race, N (%) | Caucasian | 177 (59%) | 101 (57%) | 76 (62%) | 0.12 | |||
Black | 58 (19%) | 41 (23%) | 17 (14%) | |||||
Other | 65 (22%) | 35 (20%) | 30 (24%) | |||||
mRSS—baseline, mean (SD) | Overall | 300 | 14.75 (10.72) | 177 | 20.93 (9.61) | 123 | 5.85 (3.61) | < 0.0001 |
mRSS—12 months, mean (SD) | 244 | 11.90 (9.91) | 146 | 16.10 (10.41) | 98 | 5.64 (4.17) | < 0.0001 | |
Patient Global Assessment—baseline, mean (SD) | 249 | 39.0 (26.9) | 145 | 43.5 (26.6) | 104 | 32.7 (26.1) | 0.002 | |
HAQ-DI--baseline, mean (SD) | 299 | 0.78 (0.67) | 177 | 0.99 (0.72) | 122 | 0.48 (0.49) | < 0.0001 | |
BDI,--baseline mean (SD) | 287 | 6.4 (2.2) | 171 | 6.4 (2.2) | 116 | 6.4 (2.2) | 0.97 | |
SF-36 PCS--baseline, mean (SD) | 285 | 34.7 (10.5) | 169 | 32.9 (10.6) | 116 | 37.4 (9.8) | < 0.0001 | |
SF-36 MC--baselineS, mean (SD) | 285 | 49.5 (9.9) | 169 | 48.7 (10.0) | 116 | 50.6 (9.5) | 0.11 | |
Joint contractures present at baseline, N (%) | 143 (48%) | 111 (63%) | 32 (26%) | < 0.0001 | ||||
Tendon friction rubs present at baseline, N (%) | 36 (13%) | 34 (20%) | 2 (2%) | < 0.0001 | ||||