Skip to main content

Table 1 Baseline demographics for all participants

From: Minimal Clinically Important Differences for the Modified Rodnan Skin Score: Results from the Scleroderma Lung Studies (SLS-I and SLS-II)

Variable Category Overall Diffuse SSc Limited SSc p value
N Mean (SD) N Mean (SD) N Mean (SD)
Age, mean (SD) (years)   300 50.3 (11.3) 177 49.3 (11.5) 123 51.6 (10.9) 0.08
Disease duration (years)   297 2.9 (2.0) 176 2.9 (1.9) 121 2.9 (2.1) 0.79
Gender, N (%) Male   84 (28%)   54 (31%)   30 (24%) 0.25
Female   216 (72%)   123 (69%)   93 (76%)  
SSc type, N (%) Diffuse   177 (59%)   177 (100%)   0 (0%)  
Limited   123 (41%)   0 (0%)   123 (100%)  
Race, N (%) Caucasian   177 (59%)   101 (57%)   76 (62%) 0.12
Black   58 (19%)   41 (23%)   17 (14%)  
Other   65 (22%)   35 (20%)   30 (24%)  
mRSS—baseline, mean (SD) Overall 300 14.75 (10.72) 177 20.93 (9.61) 123 5.85 (3.61) < 0.0001
mRSS—12 months, mean (SD)   244 11.90 (9.91) 146 16.10 (10.41) 98 5.64 (4.17) < 0.0001
Patient Global Assessment—baseline, mean (SD)   249 39.0 (26.9) 145 43.5 (26.6) 104 32.7 (26.1) 0.002
HAQ-DI--baseline, mean (SD)   299 0.78 (0.67) 177 0.99 (0.72) 122 0.48 (0.49) < 0.0001
BDI,--baseline mean (SD)   287 6.4 (2.2) 171 6.4 (2.2) 116 6.4 (2.2) 0.97
SF-36 PCS--baseline, mean (SD)   285 34.7 (10.5) 169 32.9 (10.6) 116 37.4 (9.8) < 0.0001
SF-36 MC--baselineS, mean (SD)   285 49.5 (9.9) 169 48.7 (10.0) 116 50.6 (9.5) 0.11
Joint contractures present at baseline, N (%)    143 (48%)   111 (63%)   32 (26%) < 0.0001
Tendon friction rubs present at baseline, N (%)    36 (13%)   34 (20%)   2 (2%) < 0.0001
  1. BDI Baseline Dyspnea Index, HAQ-DI Health Assessment Questionnaire Disability Index, mRSS modified Rodnan Skin Score, SD standard deviation, SF-36 MCS Short Form-36 Mental Component Summary, SF-36 PCS Short Form-36 Physical Component Summary, SSc systemic sclerosis