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Table 3 Disease activity and function before and after weight loss treatment in 41 patients with PsA

From: Weight loss improves disease activity in patients with psoriatic arthritis and obesity: an interventional study

 

Baseline

Median (IQR)

Min–max

6 months

Median (IQR)

Min–max

p value

Weight, kg

106.3 (95.8–113.6)

84–124

82.9 (76.4–92.1)

61.3–107.4

< 0.001

BMI, kg/m2

35.2 (34.1–38.1)

33.0–45.8

29.8 (26.6–31.5)

23.1–37.0

< 0.001

Waist circumference, cm

116 (112–122)

103–135

95.5 (89–103)

81–116

< 0.001

CRP, mg/L

4 (2–8.5)

1–50

2 (1–6.5)

1–50

0.041

Hemoglobin, g/L

144 (132–150)

116–179

141 (131.5–148)

118–161

0.047

WBC, 109/L

5.9 (5.2–7.6)

4.3–15.2

5.9 (5.0–6.8)

(3.2–12.7)

0.062

PLT, 109/L

270 (204–300)

174–444

230 (186–290)

156–402

< 0.001

Tender joints 68, score

4 (1–14)

0–30

2 (0–6.5)

0–19

< 0.001

Swollen joints 66, score

0 (0–1)

0–5

0 (0–0.5)

0–7

0.021

VAS patients global disease activity, mm

34 (19–61)

0–93

12 (5–51)

0–95

0.001

VAS pain, mm

30 (18.5–62.5)

0–95

20 (5–51.5)

0–95

0.004

VAS fatigue, mm

56 (21.5–67)

0–94

25 (8–44)

0–98

0.001

DAS28CRP, score

2.9 (2.1–3.7)

1.4–5.6

2.4 (1.7–3.0)

1.2–4.5

< 0.001

DAPSA, score

15.3 (6.6–29.1)

0.9–46

11.0 (2.8–17.6)

0.2–35

< 0.001

Leeds enthesitis index

1 (0–4)

0–6

0 (0–3)

0–4

0.001

BSA, %

1.6 (0–2.2)

0–10

0.9 (0–1.1)

0–5.5

0.014

HAQ, score

0.70 (0.13–1.00)

0–2.63

0.43 (0–0.69)

0–1.88

< 0.001

DLQI, score

1 (0–4.5)

0–17

1 (0–4)

0–20

0.453

  1. BMI body mass index, BSA body surface area, CRP C-reactive protein, DAPSA Disease Activity in PSoriatic Arthritis, DAS28CRP Disease Activity Score using 28 joint counts based on CRP, DLQI Dermatology Life Quality Index, PLT platelet count, WBC white blood cell count