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Table 3 The value of carotid ultrasound parameters for identifying disease activity

From: Value of contrast-enhanced ultrasonography of the carotid artery for evaluating disease activity in Takayasu arteritis

 

Optimal cut-point

AUC

95%CI

Sensitivity (%)

Specificity (%)

Positive likelihood ratio

Negative likelihood ratio

ESR, mm/H

20

0.782

(0.672,0.893)

71.8

62.1

1.89

0.45

CRP, mg/L

10

0.736

(0.620,0.852)

60.0

79.0

2.90

0.50

Carotid artery wall thickness, mm

1.75

0.725

(0.602,0.848)

78.9

60.7

2.01

0.35

Carotid wall vascularization grade

Grade 2

0.710

(0.586,0.834)

62.5

73.3

2.34

0.51

Combined CEUS parameters (parallel test)

0.784

(0.672,0.895)

86.8

60.7

2.21

0.22

CEUS combined ESR (serial test)

0.848

(0.751,0.944)

81.1

81.5

4.38

0.23

CEUS combined CRP (serial test)

0.821

(0.720,0.921)

73.7

74.1

2.84

0.36

  1. ESR erythrocyte sedimentation rate, CRP C-reactive protein, CEUS contrast-enhanced ultrasonography