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Table 2 Baseline patient characteristics (% or mean) for included studies in the systematic review

From: Awareness and perceived risk of cardiovascular disease among individuals living with rheumatoid arthritis is low: results of a systematic literature review

Characteristic Bartels, 2016 [10] Booc, 2016, 2017 [11, 12] Frølund, 2015 [15] van Breukelen, 2015 [14] John, 2009 [13]
n = 15 n = 208 n = 14 n = 111 n = 130
Demographics
 Female (%) 67 91 57 78 79
 Age, years (mean) 56 53 62 54 64
 Married (%) 60 57 75 62
 Post-secondary education (%) 80 30 2
 BMI, kg/m2 (mean) 23 27
Disease characteristics
 Disease activity (DAS28, mean) 2.4
 RA disease duration, years (mean) 19 7 14 16
 Positive rheumatoid factor (%) 49 58
 Positive anti-CCP antibody (%) 32 57
 Extra-articular disease present (%) 25
DMARD therapy (%) 95
Biologic DMARD therapy (%) 5
Glucocorticoid therapy (%) 65
NSAID therapy (%) 93 18
High-risk calculated CVD scorea (%) 14 40 54
CVD risk factors
 Diabetes (%) 13 7
 Cigarette smoking, ever (%) 50 5 14 57
 Hypertension (%) 40 40 14
 Hypercholesterolemia (%) 67
 Physical inactivity (%)b 76
 Prior CVD event (%) 27 4 15
 Parental history of CVD (%) 18
Lipid-lowering therapy (%) 17
Antihypertensive therapy (%) 26
Insulin/anti-diabetic therapy (%) 5
  1. Anti-CCP anti-cyclic citrullinated peptide antibody, BMI body mass index, CVD cardiovascular disease, DAS28 Disease Activity Score 28 Joints, DMARD disease-modifying anti-rheumatic drug, NSAID non-steroidal anti-inflammatory drug
  2. aHigh-risk CVD score defined as calculated Systematic COronary Risk Evaluation (SCORE) value of ≥ 20, Framingham Risk Score ≥ 10
  3. bPhysical inactivity = less than three times/week
  4. cBoo et al. 2016 and 2017 analyzed the same patient population