Fig. 2

Analgesic effects of KBP and naproxen. Analgesic effects on mechanical allodynia measured with von Frey filaments and the up-down method (a), on cold hypersensitivity measured with the acetone test (b), and on innate burrowing behavior measured with the burrowing test (c). Data in a are presented as the percent change from baseline, and data in b and c are presented as the mean change from baseline, all ± SEM, n = 10/group, using the last observation carried forward for euthanized rats. Asterisk (*) indicates statistical comparisons to CIA control.*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001