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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage

Fig. 2

Flow chart of the label-free quantitative proteomic study. Flow chart of the proteomic analysis of the kidney tissues from mice of three groups. Proteins were extracted and digested by the FASP method. The resulting peptides were analyzed by high-resolution nano-LC-MS/MS. Peptides and proteins were quantified with the label-free algorithm in MaxQuant software. The differentially proteins were further analyzed by pathway mapping and protein-protein interaction network analyses. N, C57BL/6 mice; V, vehicle mice in the treatment experiment; D, DZ2002-treated mice in the treatment experiment

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