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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Tolerogenic XCR1+ dendritic cell population is dysregulated in HLA-B27 transgenic rat model of spondyloarthritis

Fig. 5

The XCR1+CD4 cDC population is decreased in B27-Tg rat colonic lamina propria. Cells were isolated from the colonic lamina propria of 6–9-month-old rats, marked for CD103, CD4, and XCR1 and analyzed by flow cytometry. a Representative dot-plots showing the expression of CD4 among CD103+ cDCs in NTG and B27-Tg rats. b, c The graphs show the frequency (b) and absolute number (c) of CD4 among CD103+ cDCs in NTG and B27-Tg rats. d Representative dot-plots showing the expression of XCR1 among CD103+ cDCs in NTG and B27-Tg rats. e, f The graphs show the frequency (e) and absolute number (f) of XCR1+ cDCs among CD103+ CD4 cDCs in NTG and B27-Tg rats. The experiment was repeated 7 times. Bars show the mean ± SEM. Data were analyzed by unpaired Student’s t test

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