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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Upregulation of miR-107 expression following hyperbaric oxygen treatment suppresses HMGB1/RAGE signaling in degenerated human nucleus pulposus cells

Fig. 2

Seed sequence of miR-107 in the 3′ UTR of the HMGB1 mRNA. a MiRnalyze predicted the duplex of miR-107 with its seed sequence in the 3′ UTR of the human HMGB1 mRNA. b TargetScan predicted the duplex of miR-107 with the seed sequence in the 3′ UTR of the human HMGB1 mRNA. The sequences in white are the locations of the potential seed-matched sequences for the miRNAs assessed. c Cross-species conservation of the miR-107 seed sequence in the 3′ UTR of the human HMGB1 mRNA as identified via the TargetScan algorithm (sequences in red)

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