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Fig. 8 | Arthritis Research & Therapy

Fig. 8

From: Upregulation of miR-107 expression following hyperbaric oxygen treatment suppresses HMGB1/RAGE signaling in degenerated human nucleus pulposus cells

Fig. 8

Effect of HBO on MMP-3, MMP-9, and MMP-13 secretion. a HBO treatment significantly inhibited MMP-3 secretion (p > 0.05, *p < 0.05, **p < 0.01; n = 4) by degenerated NPCs. b HBO treatment significantly inhibited MMP-9 secretion (p > 0.05, *p < 0.05, **p < 0.01; n = 4) by degenerated NPCs. c HBO treatment significantly inhibited MMP-13 secretion (p > 0.05, *p < 0.05, **p < 0.01; n = 4) by degenerated NPCs. The observed regulation of these MMPs could likely be a result of the decreased MAPK and NF-kB signaling following HBO treatment

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Arthritis Research & Therapy

ISSN: 1478-6362

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