Fig. 2

Impact of enthesitis or dactylitis resolution at week 24. Data are from integrated analysis sets of patients with baseline enthesitis and dactylitis. LS mean change from baseline (SE) of EQ-5D VAS (a) and HAQ-DI (b) scores in patients with enthesitis or dactylitis resolution. c Percentages of patients (NRI) with enthesitis or dactylitis resolution reporting improvement meeting or exceeding the MCID of the HAQ-DI (≥ 0.35). d Mean change from baseline (LOCF) (SD) of pain VAS. Only one side of the error bar is shown. Abbreviations: EQ-5D VAS, EuroQol-5 Dimensions Visual Analogue Scale; HAQ-DI, Health Assessment Questionnaire-Disability Index; LDI-B, Leeds Dactylitis Index-Basic; LEI, Leeds Enthesitis Index; LOCF, last observation carried forward; LSM, least squares mean; MCID, minimal clinically important difference; N, population size; n, number in group; NRI, nonresponder imputation; SD, standard deviation; SE, standard error; VAS, visual analogue scale