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Table 3 Baseline bone mineral density measured by DEXA and DXR, by groups with anti-CCP > 500 IU/ml and anti-CCP negative

From: Anti-citrullinated protein antibodies are associated with osteopenia but not with pain at diagnosis of rheumatoid arthritis: data from the BARFOT cohort

 

All patients

Women

Men

Anti-CCP

p value

Anti-CCP

p value

Anti-CCP

p value

> 500 IU/ml

Negative

> 500 IU/ml

Negative

> 500 IU/ml

Negative

n = 180

n = 277

n = 103

n = 183

n = 77

n = 94

DEXA

 

Lumbar spine

 z-score, mean (SD)

− 0.57

(1.22)

− 0.48

(1.36)

0.53

− 0.53

(1.19)

− 0.53

(1.25)

0.97

− 0.63

(1.27)

− 0.37

(1.55)

0.32

 Osteopenia, %

33

36

0.56

31

36

0.52

35

37

0.85

Femoral neck

 z-score, mean (SD)

− 0.10

(1.10)

0.02

(0.96)

0.32

− 0.04

(1.18)

− 0.10

(0.89)

0.69

− 0.19

(0.99)

0.28

(1.05)

0.027

 Osteopenia, %

23

9

0.002

22

9

0.028

24

8

0.036

Femoral Ward

 z-score, mean (SD)

− 0.19

(1.12)

0.18

(1.16)

0.01

− 0.19

(1.23)

0.10

(1.10)

0.13

− 0.20

(0.96)

0.35

(1.25)

0.020

 Osteopenia, %

22

9

0.004

23

10

0.035

20

6

0.043

Femoral trochanter

 z-score, mean (SD)

− 0.06

(1.16)

0.16

(1.02)

0.13

− 0.03

(1.30)

0.05

(0.98)

0.68

− 0.10

(0.93)

0.37

(1.08)

0.032

 Osteopenia, %

20

14

0.18

23

17

0.40

17

7

0.13

DXR, metacarpal

 z-score, mean (SD)

0.01

(1.08)

− 0.03

(1.13)

0.80

− 1.13

(1.23)

− 0.29

(1.12)

0.40

0.13

(0.91)

0.45

(1.01)

0.09

 Osteopenia, %

17

20

0.34

23

26

0.40

12

8

0.40

  1. p values denote differences between groups, and italicized values are significant
  2. DEXA dual-energy X-ray absorptiometry, DXR digital X-ray radiogrammetry