A/G norms | TCZ-QW + Pred-26 N = 100 | PBO + Pred-26 N = 50 | PBO + Pred-52 N = 51 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
p value | p value | |||||||||||
BL | Wk 52 | LSM Δ BL–Wk 52 | BL | Wk 52 | LSM Δ BL–Wk 52 | TCZ-QW + Pred-26 vs PBO + Pred-26 | BL | Wk 52 | LSM Δ BL–Wk 52 | pTCZ-QW + Pred-26 vs PBO + Pred-52 | ||
PF | 67.56 | 69.10 n = 100 | 78.28 n = 85 | 6.83 n = 98 | 63.60 n = 50 | 63.48 n = 43 | − 3.43 n = 49 | 0.0024 | 59.40 n = 50 | 65.44 n = 45 | 2.68 n = 50 | NS |
RP | 69.44 | 49.56 n = 100 | 73.75 n = 85 | 20.64 n = 98 | 52.42 n = 49 | 58.28 n = 43 | 5.87 n = 48 | < 0.001 | 45.38 n = 50 | 53.89 n = 45 | 4.46 n = 50 | < 0.001 |
BP | 64.52 | 61.93 n = 100 | 73.25 n = 85 | 10.89 n = 98 | 58.90 n = 50 | 61.77 n = 43 | 1.00 n = 49 | NS | 55.67 n = 49 | 56.27 n = 45 | − 2.87 n = 49 | < 0.001 |
GH | 66.49 | 55.00 n = 97 | 65.81 n = 85 | 9.06 n = 95 | 56.43 n = 49 | 57.28 n = 43 | − 1.34 n = 48 | < 0.001 | 55.69 n = 50 | 52.29 n = 45 | − 4.05 n = 50 | < 0.001 |
VT | 58.65 | 50.19 n = 99 | 66.13 n = 85 | 15.69 n = 97 | 49.00 n = 50 | 55.67 n = 43 | 5.26 n = 49 | 0.0011 | 42.38 n = 50 | 49.17 n = 45 | 3.53 n = 50 | < 0.001 |
SF | 81.49 | 64.25 n = 100 | 84.71 n = 85 | 17.35 n = 98 | 65.25 n = 50 | 75.87 n = 43 | 9.83 n = 49 | NS | 63.00 n = 50 | 67.50 n = 45 | 2.34 n = 50 | < 0.001 |
RE | 82.08 | 66.38 n = 100 | 82.45 n = 85 | 13.37 n = 98 | 64.63 n = 49 | 74.81 n = 43 | 6.44 n = 48 | NS | 60.33 n = 50 | 69.63 n = 45 | 3.53 n = 50 | NS |
MH | 77.16 | 64.04 n = 99 | 77.94 n = 85 | 12.54 n = 97 | 64.20 n = 50 | 73.60 n = 43 | 7.43 n = 49 | NS | 59.10 n = 50 | 66.33 n = 45 | 3.13 n = 50 | < 0.001 |
SF-6D utility score | 0.746 | 0.694 | 0.775 | 0.080 | 0.686 | 0.721 | 0.034 | – | 0.663 | 0.692 | 0.029 | – |