Table 2 Factors related to SF36-MCS and PCS over 5 to 8 years in early arthritis (EA) and early inflammatory back pain (IBP): results of univariate mixed linear models
Characteristics associated to HRQoL | EA | Early IBP | ||
|---|---|---|---|---|
MCS beta (p value) | PCS beta (p value) | MCS beta (p value) | PCS beta (p value) | |
Baseline characteristics | ||||
Age | − 0.0049 (0.055) | − 0.0086 (0.001) | − 0.00031 (0.69) | − 0.0017 (0.003) |
Gender | − 0.0056 (0.93) | + 0.041 (0.50) | + 0.00075 (0.96) | + 0.016 (0.12) |
Level of studies | − 0.029 (0.66) | + 0.20 (0.003) | − 0.013 (0.33) | + 0.017 (0.11) |
Level employment | + 0.017(0.82) | + 0.12 (0.04) | + 0.026 (0.06) | − 0.010 (0.32) |
Baseline MCS-SF36 | − 0.041 (< 0.001) | + 0.0012 (0.007) | − 0.0083 (< 0.001) | + 0.0013 (0.004) |
Baseline PCS-SF36 | − 0.0048 (0.19) | − 0.038 (< 0.001) | − 0.00001 (0.99) | − 0.0052 (< 0.0001) |
Smoking status | − 0.097 (0.11) | − 0.049 (0.33) | + 0.0058 (0.68) | + 0.0077 (0.46) |
HLAB27 status | NA | NA | + 0.011 (0.42) | − 0.0062 (0.54) |
Radiological or MRI sacroiliitis | NA | NA | − 0.012 (0.39) | + 0.016 (0.12) |
Symptom duration | + 0.0012 (0.04) | + 0.0025 (< 0.001) | + 0.0062 (0.42) | − 0.015 (0.008) |
Variables changing over time | ||||
Erosions on hands and/or feet | + 0.54 (0.19) | + 0.32 (0.36) | NA | NA |
Oral corticosteroid | + 0.13 (0.10) | + 0.20 (0.002) | NA | NA |
DMARDs | + 0.36 (< 0.001) | + 0.61 (< 0.001) | NA | NA |
DAS28-ESR/ASDAS-CRP | + 0.20 (< 0.001) | + 0.27 (< 0.001) | + 0.0062 (0.39) | − 0.016 (0.0005) |
Extra articular manifestations† | NA | NA | − 0.0037 (0.80) | + 0.00001 (1.00) |
Peripheral arthritis | NA | NA | + 0.029 (0.04) | + 0.018 (0.09) |
Enthesitis | NA | NA | + 0.014 (0.36) | + 0.015 (0.19) |
TNFi | NA | NA | − 0.021 (0.21) | − 0.027 (0.03) |