Skip to main content

Advertisement

Table 1 Baseline characteristics of patients with rheumatic diseases and healthy controls

From: Health-related quality of life in systemic sclerosis compared with other rheumatic diseases: a cross-sectional study

  Group
SSc
(n = 120)
RA
(n = 120)
SLE
(n = 120)
SjS
(n = 120)
Control
(n = 600)
P value*
Age, years, mean (SD) 57.2 (11.2) 58.3 (12.1) 43.0 (14.1) 58.7 (10.9) 44.9 (15.3) < 0.001
Female, n (%) 106 (88.3) 107 (89.2) 107 (89.2) 116 (96.7) 303 (50.5) < 0.001
Disease duration, years, mean (SD) 11.7 (23.2) 7.6 (6.5) 8.3 (5.6) 6.4 (4.9) NA < 0.001
Comorbidities, n (%)
 Hypertension 39 (32.5) 38 (31.7) 24 (20.0) 24 (20.0) 99 (16.5) < 0.001
 Diabetes mellitus 12 (10.0) 8 (6.7) 8 (6.7) 7 (5.8) 39 (6.5) 0.713
 Dyslipidemia 10 (8.3) 17 (14.2) 19 (15.8) 12 (10.0) 31 (5.2) < 0.001
 Ischemic heart disease 6 (5.0) 3 (2.5) 0 (0) 4 (3.3) 5 (0.8) 0.004
 Chronic liver diseases 3 (2.5) 4 (3.3) 7 (5.8) 3 (2.5) 10 (1.7) 0.098
 Renal diseases 0 (0) 2 (1.7) 33 (27.5) 4 (3.3) 4 (0.7) < 0.001
 Thyroid diseases 12 (10.0) 8 (6.7) 8 (6.7) 13 (10.8) 6 (1.0) < 0.001
Education, n (%)       < 0.001
 University 39 (32.5) 45 (37.5) 69 (57.5) 51 (42.5) 221 (36.8)  
 High school 30 (25.0) 45 (37.5) 37 (30.8) 43 (35.8) 278 (46.3)  
 Middle school 17 (14.2) 13 (10.8) 7 (5.8) 14 (11.7) 49 (8.2)  
 Primary school 21 (17.5) 12 (10.0) 4 (3.3) 11 (9.2) 52 (8.7)  
 Uneducated 0 (0) 1 (0.8) 1 (0.8) 1 (0.8) 0 (0)  
BMI, kg/m2, mean (SD) 20.6 (4.5) 22.8 (3.0) 22.8 (3.9) 22.6 (5.1) 23.4 (13.2) 0.127
Alcohol, n (%) 16 (13.6) 24 (20.0) 32 (26.7) 18 (15.0)   < 0.001
Smoking, n (%) 8 (6.8) 11 (9.2) 11 (9.2) 4 (3.3)   0.252
Laboratory findings, mean (SD)
 WBC, mm3 7258.6 (202.3) 8079.2 (11,302.2) 5598.1 (2399.8) 5427.7 (1852.2)   0.001
 Hemoglobin, g/dL 12.4 (1.4) 12.7 (1.2) 12.4 (1.5) 12.4 (1.2)   0.229
 Platelet, mm3 240.3 (66.9) 266.2 (64.5) 224.3 (75.2) 217.9 (71.9)   < 0.001
 AST, IU/L 23.3 (8.6) 22.6 (9.5) 24.3 (15.2) 24.6 (8.1)   0.473
 ALT, IU/L 18.0 (12.3) 20.0 (13.5) 22.6 (24.4) 19.2 (10.9)   0.159
 BUN, mg/dL 13.8 (8.2) 14.4 (5.8) 13.7 (6.6) 14.5 (6.3)   0.731
 Creatinine, mg/dL 0.9 (1.1) 0.9 (1.6) 0.8 (0.3) 0.9 (1.2)   0.810
 ESR, mm/h 30.6 (21.2) 30.6 (20.7) 27.4 (21.5) 27.9 (23.6)   0.520
 Hs-CRP, mg/L 0.5 (1.1) 0.6 (1.0) 0.3 (0.5) 0.4 (1.7)   0.378
  1. SD, standard deviation; SSc, systemic sclerosis; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; SjS, Sjogren’s syndrome; BMI, body mass index; WBC, white blood cell; AST, aspartate transaminase; ALT, alanine transaminase; BUN, blood urea nitrogen; ESR, erythrocyte sedimentation rate; hs-CRP, high sensitivity C-reactive protein
  2. *For continuous variables, statistical significance was tested with one-way analyses of variance and the Scheffe multiple comparison test