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Table 3 Comparison between survivors and non-survivors with IM

From: Invasive mycoses in patients with connective tissue disease from Southern China: clinical features and associated factors

Characteristics

Survivor (n = 22)

Non-survivor (n = 10)

P value

Demographic characteristics

 Sex, male to female

4:18

3:7

0.45

 Age, years, mean ± SD

41.6 ± 15.6

44.2 ± 16.8

0.68

 Diabetes mellitus, n (%)

2(9.1)

2(20.0)

0.39

 Interstitial pneumonia, n (%)

4(18.2)

2(20.0)

0.90

 Nephritis, n (%)

12(54.5)

7(70.0)

0.41

Laboratory data

 Leukopenia, n (%)

1(4.5)

3(30.0)

0.04*

 Lymphopenia, n (%)

13(59.1)

10(100)

0.02*

 Anemia, n (%)

12(54.5)

8(80.0)

0.17

 Hypoalbuminemia, n (%)

14(63.6)

9(90.0)

0.12

 Elevated serum creatinine, n (%)

6(27.3)

7(70.0)

0.02*

 Co-infection, n (%)

4(18.2)

7(70.0)

0.004*

 Co-infection with multiple agents, n (%)

1(4.5)

2(20.0)

0.22

 Co-infection in multiple sites, n (%)

0(0)

5(50.0)

< 0.001*

Treatments prior to IM

 Median-to-high dose of GC, n (%)

7(31.8)

4(40.0)

0.65

 CYC, n (%)

4(18.2)

5(50.0)

0.06

 MMF, n (%)

1(4.5)

2(20.0)

0.16

  1. CYC cyclophosphamide, GC glucocorticoid, IM invasive mycoses, MMF mycophenolate mofetil, SD standard deviation
  2. *Significant