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Table 4 Comparison between patients with or without IM

From: Invasive mycoses in patients with connective tissue disease from Southern China: clinical features and associated factors

Characteristics Case (n = 32) Control (n = 64) P value
Demographic characteristics
 Sex, male to female 7:25 15:49 0.86
 Age, years, mean ± SD 42.4 ± 15.8 45.5 ± 17.5 0.44
 Duration of CTD, months, median (IQR) 6.0(1.0,75.0) 24.0(7.5,87.0) 0.19
 Diabetes mellitus, n (%) 4(12.5) 3(4.7) 0.17
 Interstitial pneumonia, n (%) 6(18.8) 2(3.1) 0.01*
 Nephritis, n (%) 19(59.4) 29(45.3) 0.19
Laboratory data
 Leukopenia, n (%) 4(12.5) 11(17.2) 0.55
 Lymphopenia, n (%) 23(71.9) 27(42.2) 0.01*
 Anemia, n (%) 20(62.5) 38(59.4) 0.77
 Hypoalbuminemia, n (%) 23(71.9) 42(75.0) 0.75
 Elevated serum creatinine, n (%) 13(40.6) 18(28.1) 0.22
 IgM (g/l), median (IQR) 0.6(0.3,1.0) 0.8(0.5,1.3) 0.09
 IgG (g/l), median (IQR) 14.1(10.3,17.3) 13.1(8.9,17.9) 0.77
 ESR (mm/h),median (IQR) 56.0(40,66) 27.0(13,58) 0.01*
 CRP (mg/l), median (IQR) 11.7(5.0,37.0) 2.9(0.9,14.3) 0.002*
Treatments prior to IM
 Median-to-high dose of GC, n (%) 11(34.4) 6(9.4) < 0.001*
 CYC, n (%) 9(28.1) 8(12.5) 0.06
 MMF, n (%) 3(9.4) 8(12.5) 0.65
 CsA, n (%) 3(9.4) 8(12.5) 0.65
 MTX, n (%) 2(6.3) 6(9.4) 0.60
  1. CRP C-reactive protein, CsA cyclosporine A, CTD connective tissue disease, CYC cyclophosphamide, ESR erythrocyte sedimentation rate, GC glucocorticoid, IM invasive mycoses, IQR interquartile range, MMF mycophenolate mofetil, MTX methotrexate, SD standard deviation
  2. *Significant