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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Full high-throughput sequencing analysis of differences in expression profiles of long noncoding RNAs and their mechanisms of action in systemic lupus erythematosus

Fig. 5

SLE patients exhibit a strong gender bias and a robust “IFN signature.” a TSIX expressions in PBMCs of 19 patients with SLE and 37 healthy donors (NC) were analyzed by qPCR. b TSIX expressions in PBMCs of 13 male SLE patients and 26 female SLE patients were analyzed by qPCR. **P < 0.01, ***P < 0.001, ****P < 0.0001. c IFN-α expressions in the serum of 12 patients with inactive SLE, 21 patients with active SLE, and 20 healthy donors (NC) were analyzed by ELISA. ***P < 0.001, ****P < 0.0001. d Nonparametric correlation (Spearman) was performed to assess the correlation between IFN-α and SLEDAI score in patients with SLE (n = 33)

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