Fig. 2

Exemplary depiction of the three imaging techniques: a Nailfold Capillaroscopy of a patient with diffuse SSc; the last capillary line is disorganized, the capillaries are rarefied (late pattern). b Colour Doppler ultrasonography shows a narrowed PPDA in a patient with diffuse SSc. c Fluorescence optical imaging in a patient with diffuse SSc; the index finger of the left hand shows a missing ICG enhancement as a sign of perturbed perfusion. SSc—systemic sclerosis; PPDA—proper palmar digital artery; ICG—indocyanine green