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Table 2 Correlation between serum IFN activity; levels of IFN-α, IFN-γ and IFN-λ1; disease activity and damage

From: High levels of circulating interferons type I, type II and type III associate with distinct clinical features of active systemic lupus erythematosus

Parameter

IFN activity (ρ)

p value

IFN-γ (ρ)

p value

IFN-α

0.25

< 0.0001

0.2

0.009

IFN-γ

0.4

< 0.0001

–

–

IFN-λ1

0.12

0.04

0.05

ns

SLAM

0.3

< 0.0001

0.08

ns

SLEDAI

0.3

< 0.0001

0.14

0.005

SDI

− 0.13

0.003

− 0.02

ns

Prednisone dose

0.07

ns

− 0.06

ns

  1. Statistical analysis was performed by Spearman rank correlation test. Results are presented as Spearman rank correlation coefficient (ρ)
  2. SLAM Systemic Lupus Activity Measure, SLEDAI SLE Disease Activity Index, SDI SLE disease damage index
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Arthritis Research & Therapy

ISSN: 1478-6362

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