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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Antifibrotic effects of 2-carba cyclic phosphatidic acid (2ccPA) in systemic sclerosis: contribution to the novel treatment

Fig. 6

2ccPA suppressed the development of bleomycin-induced skin fibrosis in mice. a Representative histological sections in skin biopsies of mice treated with PBS, bleomycin (Bleo), Bleo+2ccPA 1 mg/kg, or Bleo+2ccPA 10 mg/kg. Scale bar = 100 μm. b Skin thickness, collagen content, and αSMA-positive cells of each group. Each group consisted of eight mice. Bars represent the mean ± SD. *p < 0.05

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