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Table 5 Paired association between PCV-13 serotype-specific IgG and OI

From: Evaluation of pneumococcal and tetanus vaccine responses in patients with rheumatoid arthritis receiving baricitinib: results from a long-term extension trial substudy

 

Serotype 4

N = 98

Serotype 6B

N = 100

Serotype 14

N = 100

Serotype 23F

N = 100

≥ 2-fold increase in pneumococcal IgG and functional OI

46 (47)

57 (57)

32 (32)

56 (56)

≥ 2-fold increase in pneumococcal IgG, but not functional OI

4 (4)

6 (6)

8 (8)

3 (3)

≥ 2-fold increase in functional OI, but not pneumococcal IgG

28 (29)

19 (19)

15 (15)

17 (17)

< 2-fold increase in both pneumococcal IgG and functional OI

20 (20)

18 (18)

45 (45)

24 (24)

  1. Data are reported as n (%)
  2. IgG immunoglobulin G, OI opsonization index, PCV-13 13-serotype pneumococcal conjugate vaccine