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Table 5 Paired association between PCV-13 serotype-specific IgG and OI

From: Evaluation of pneumococcal and tetanus vaccine responses in patients with rheumatoid arthritis receiving baricitinib: results from a long-term extension trial substudy

  Serotype 4
N = 98
Serotype 6B
N = 100
Serotype 14
N = 100
Serotype 23F
N = 100
≥ 2-fold increase in pneumococcal IgG and functional OI 46 (47) 57 (57) 32 (32) 56 (56)
≥ 2-fold increase in pneumococcal IgG, but not functional OI 4 (4) 6 (6) 8 (8) 3 (3)
≥ 2-fold increase in functional OI, but not pneumococcal IgG 28 (29) 19 (19) 15 (15) 17 (17)
< 2-fold increase in both pneumococcal IgG and functional OI 20 (20) 18 (18) 45 (45) 24 (24)
  1. Data are reported as n (%)
  2. IgG immunoglobulin G, OI opsonization index, PCV-13 13-serotype pneumococcal conjugate vaccine