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Table 1 Characteristics of individual articles selected

From: A simplified lung ultrasound for the diagnosis of interstitial lung disease in connective tissue disease: a meta-analysis

First author [Ref] Year Country Disease LIS Numbers Cutoff value (B-line) Probe frequency (MHz) Probe type True positive False positive False negative True negative Study quality
ILD (+) ILD (−)
Delle [32] 2010 Italy SSc 65 16 11 5 2.5–3.5; 6–12 2.5–3.5 (cardiac sector probe); 6–12 (linear probe) 12 2 4 9 7
Tardella [10] 2012 Italy CTD 50 26 8 10 2–7 Broadband convex multi-frequency transducer 20 0 6 8 13
Barskova [24] 2013 Italy SSc 72 36 22 5 2.5–3.5 Cardiac sector transducer 36 10 0 12 13
Mohammadi [33] 2014 USA SSc 10 53 17 5 7–10 Broadband linear multi-frequency transducer 39 2 14 15 11
Moazedi-Fuerst [34] 2014 Austria RA All 17 47 3.5 Convex transducer 16 2 1 45 11
Cogliati [7] 2014 Italy RA 72 13 26 10 5–2 Convex probe 12 13 1 13 13
Moazedi-Fuerst(a) [23] 2015 Austria RA All 7 18 3.5 Convex transducer 7 1 0 17 10
Moazedi-Fuerst(b) [23] 2015 Austria SSc All 9 5 3.5 Convex transducer 9 2 0 3 10
Moazedi-Fuerst(c) [23] 2015 Austria SLE All 4 2 3.5 Convex transducer 4 0 0 2 10
Vizioli [35] 2016 Italy ILD All 25 24 5 5–8; 2–5 5–8 (linear probe); 2–5 (convex probe) 23 7 2 17 14
Cakir [29] 2016 Turkey SSc 14 29 19 5 5–10 Linear probe 29 3 0 16 11
Vasco [8] 2017 Spain SS All 4 9 3 2–5.5; 3.3–10 2–5.5 (60-mm-wide-band convex array probe); 3.3–10 (linear array) 4 1 0 8 14
Tardella [9] 2018 Italy SSc 14 27 13 10 4–13 Broadband linear transducer 26 1 1 12 14
  1. a, b, and c represent one article including three different diseases
  2. ILD interstitial lung disease, CTD connective tissue disease, SSc systemic sclerosis, RA rheumatoid arthritis, SLE systemic lupus erythematosus, SS Sjögren’s syndrome, LIS intercostal spaces, − not available