Advertisement
Table 4 Diagnostic accuracy of LUS in different LIS
| Different LIS | Study no. | Number | Sensitivity (95% CI) | Heterogeneity | Specificity (95% CI) | Heterogeneity | PLR (95% CI) | NLR (95% CI) | DOR (95% CI) | AUC (SE) | Q* (SE) | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ILD (+) | ILD (−) | I 2 | p value | I 2 | p value | |||||||||
| Total | 11 | 266 | 221 | 0.859 (0.812–0.898) | 62.8 | 0.001 | 0.839 (0.782–0.886) | 68.1 | 0 | 5.412 (3.026–9.680) | 0.176 (0.111–0.279) | 43.16 (22.58–82.52) | 0.934 (0.017) | 0.871 (0.021) |
| All | 4 | 68 | 105 | 0.955 (0.873–0.991) | 0 | 0.721 | 0.876 (0.798–0.932) | 59.6 | 0 | 5.476 (2.597–11.55) | 0.086 (0.035–0.211) | 59.76 (21.05–1525.8) | 0.975 (0.016) | 0.927 (0.027) |
| 72 | 2 | 49 | 48 | 0.814 (0.691–0.903) | 35.0 | 0.215 | 0.358 (0.486–0.804) | 92.2 | 0 | 3.367 (1.810–6.621) | 0.208 (0.110–0.396) | 25.57 (5.183–146.7) | – | – |
| 65 | 1 | 16 | 11 | 0.75 (0.48–0.93) | – | – | 0.82 (0.48–0.98) | – | – | 4.13 (1.14–14.91) | 0.31 (0.13–0.75) | 13.50 (2.01–90.69) | – | – |
| 50 | 1 | 26 | 8 | 1.000 (0.398–1.000) | – | – | 1.000 (0.158–1.000) | – | – | 5.400 (0.423–68.96) | 0.120 (0.008–1.746) | 45.00 (0.666–3042.6) | – | – |
| 14 | 2 | 56 | 32 | 0.982 (0.904–1.000) | 32.4 | 0.224 | 0.875 (0.710–0.965) | 0 | 0.485 | 7.297 (3.050–17.45) | 0.029 (0.006–0.147) | 292.30 (35.53–2403.8) | – | – |
| 10 | 1 | 53 | 17 | 0.736 (0.597–0.847) | – | – | 0.882 (0.636–0.985) | – | – | 6.255 (1.685–23.223) | 0.299 (0.185–0.485) | 20.893 (4.232–103.15) | – | – |
