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Table 5 Summary diagnostic accuracy of LUS in different diseases

From: A simplified lung ultrasound for the diagnosis of interstitial lung disease in connective tissue disease: a meta-analysis

Disease Study no. Numbers Sensitivity (95% CI) Heterogeneity Specificity (95% CI) Heterogeneity PLR (95% CI) NLR (95% CI) DOR (95% CI) AUC (SE) Q* (SE)
ILD (+) ILD (−) I 2 p value I 2 p value
SSc 6 170 87 0.839 (0.777–0.889) 78.3 0 0.870 (0.774–0.936) 21.4 0.272 6.203 (3.565–10.800) 0.191 (0.098–0.373) 42.93 (17.75–103.79) 0.929 (0.024) 0.864 (0.029)
RA 3 37 91 0.946 (0.818–0.993) 0 0.636 0.824 (0.730–0.896) 91.8 0 7.398 (0.768–74.220) 0.082 (0.024–0.275) 80.24 (8.107–796.09) 0.9810 (0.014) 0.939 (0.027)
  1. CTD connective tissue disease, ILD interstitial lung disease, SSc systemic sclerosis, RA rheumatoid arthritis, PLR positive likelihood ratio, NLR negative likelihood ratio, DOR diagnostic OR, AUC area under the curve, CI confidence interval, SE standard error, − not available