Low plasma concentrations of apolipoprotein M are associated with disease activity and endothelial dysfunction in systemic lupus erythematosus

Table 5 Plasma levels of apoM in SLE patients with disease activity in different organ systems

SLEDAI-2 K items^a	apoM	n+	apoM	n−	p
Arthritis	0.82	20	0.70	64	0.37
Glomerulonephritis^b	0.55	21	0.76	63	< 0.01
Rash	0.55	29	0.80	55	0.01
Low complement	0.67	37	0.75	46	0.06
Anti-dsDNA antibodies	0.54	24	0.78	60	< 0.01
Fever	0.59	9	0.73	75	0.33
Thrombocytopenia	0.92	5	0.70	79	0.73
Leukopenia	0.50	13	0.76	71	< 0.01
Alopecia	0.66	8	0.72	76	0.78

Median plasma concentrations (μM) of apoM in SLE patients in patients group I (n = 84) with (n+) and without (n−) different items in SLEDAI-2 K
^aOnly items with n ≥ 5 included
^bUrinary casts, proteinuria, hematuria, or pyuria

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