Table 1 Top 20 most significantly differentially expressed genes when comparing the transcriptomes of the bone marrow mesenchymal stem cells (BM-MSCs) exposed to activated peripheral blood mononuclear cells (PBMCs) from rheumatoid arthritis patients and BM-MSCs exposed to resting PBMCs from RA patients. Positive logarithm of the fold change (Log2FC) indicates greater expression on BM-MSCs exposed to activated PBMCs
Entrez ID | Symbol | Log2FC | FDR |
|---|---|---|---|
4317 | MMP8 | 11.4 | 3.74E−05 |
3620 | IDO1 | 9.8 | 3.74E−05 |
115362 | GBP5 | 9.5 | 3.74E−05 |
3055 | HCK | 8.4 | 3.74E−05 |
5452 | POU2F2 | 6.5 | 3.74E−05 |
1440 | CSF3 | 12.4 | 4.66E−05 |
6364 | CCL20 | 9.9 | 7.44E−05 |
3553 | IL1B | 9.7 | 7.44E−05 |
84419 | C15orf48 | 9.2 | 7.44E−05 |
64127 | NOD2 | 9.0 | 7.44E−05 |
115361 | GBP4 | 6.5 | 7.44E−05 |
272 | AMPD3 | 5.7 | 7.44E−05 |
9235 | IL32 | 5.2 | 7.44E−05 |
6352 | CCL5 | 8.5 | 9.68E−05 |
261729 | STEAP2 | 5.2 | 1.06E−04 |
2537 | IFI6 | 4.6 | 1.06E−04 |
4939 | OAS2 | 3.7 | 1.08E−04 |
2919 | CXCL1 | 10.3 | 1.15E−04 |
165904 | XIRP1 | 8.1 | 1.15E−04 |
29015 | SLC43A3 | 4.8 | 1.15E−04 |