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Fig. 10 | Arthritis Research & Therapy

Fig. 10

From: Increased peptidylarginine deiminases expression during the macrophage differentiation and participated inflammatory responses

Fig. 10

Effects of PADI inhibitors on proinflammatory cytokines secretion in human monocyte-derived macrophages stimulated with lipopolysaccharides (LPS). Human monocyte-derived macrophages cocultured with LPS alone or LPS with 10 μM sanguinarine (SANG), 10 μM ruthenium red (RUR), or 10 μM Cl-amidine for 24 h. The culture soups were collected for further analysis of a TNF-α, b IL-1β, and c IL-6 concentration using ELISA. #P < 0.05 compared with human monocyte-derived macrophages stimulated with LPS

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