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Fig. 8 | Arthritis Research & Therapy

Fig. 8

From: Increased peptidylarginine deiminases expression during the macrophage differentiation and participated inflammatory responses

Fig. 8

Using short hairpin (sh) RNA to inhibit the expression of PADI2 and its effect on citrullinated PAI-2 (citPAI-2) protein levels. a Protein levels citPAI-2 did not change in U937 cells transfected with PADI2 shRNA plasmid compared with the controls (empty plasmid). b Protein levels of citPAI-2 decreased in differentiated macrophages transfected with PADI2 shRNA plasmid compared with the controls. c Protein levels of citPAI-2 decreased in macrophages stimulated with LPS transfected with PADI2 shRNA plasmid compared with the controls

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