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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Differential synovial tissue biomarkers among psoriatic arthritis and rheumatoid factor/anti-citrulline antibody-negative rheumatoid arthritis

Fig. 4

ae IHC staining for CD31 on ST of patients with naïve or MTX-IR PsA and Abneg RA patients. Example photos of CD31 (DAB) staining of ST biopsies from patients with naïve (a) or MTX-IR (b) PsA and with naïve (c) or MTX-IR (d) Abneg RA (magnification × 20 and magnification × 40 in the corresponding inset). Thin black arrows indicate CD31+ vessels (brown) in the corresponding inset. e Synovial CD31+ vessel count in PsA and Abneg RA patients divided by treatment regimen; *p = 0.01, naïve vs MTX-IR PsA patients; *p < 0.001, naïve vs MTX-IR Abneg RA patients. IHC immunohistochemistry, PsA psoriatic arthritis, RA rheumatoid arthritis, Ab autoantibody, MTX-IR methotrexate inadequately responder, CD cluster designation

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