Symptomatic bone marrow lesions induced by reduced bone mineral density in middle-aged women: a cross-sectional Japanese population study

Table 4 Relationships between BMLs and bone markers

Total sample (n = 266)	R² (adjusted)	β	p value	95% CI
BAP	0.135	0.193	0.003	0.002 to 0.011
PINP	0.123	0.142	0.022	0.000 to 0.003
NTx	0.121	0.128	0.032	0.000 to 0.009
TRACP-5b	0.131	0.194	0.006	0.000 to 0.000
Pentosidine	0.106	0.011	0.852	− 0.002 to 0.002
Homocysteine	0.106	− 0.022	0.708	− 0.009 to 0.006

Statistical analysis—multiple linear regression analysis. Dependent variables—the natural logs of BML score plus 5. Independent variables—age, BMI, and bone markers (BAP, PINP, NTx, TRACP-5b, pentosidine, and homocysteine)
BMLs bone marrow lesions, BAP bone-specific alkaline phosphatase, PINP procollagen type I N-terminal propeptide, NTx crosslinked N-telopeptide of type I collagen, TRACP-5b tartrate-resistant acid phosphatase-5b, R² coefficient of determination, β standardized regression coefficient, CI confidence interval

ISSN: 1478-6362