Fig. 3
From: The RIG-I pathway is involved in peripheral T cell lymphopenia in patients with dermatomyositis
The RIG-I expression level increased significantly in peripheral T lymphocytes and correlated negatively with T lymphocyte count in DM. a Western blotting analysis of RIG-I expression in peripheral T lymphocytes of DM patients and healthy controls (HC). DM patients exhibited significantly higher levels of RIG-I mRNA and RIG-I protein. b The RIG-I mRNA and protein expression level in T lymphocytes of patients with lymphopenia were significantly higher than those of the patients without lymphopenia. c The protein and gene protein expression level of RIG-I correlated negatively with lymphocyte count and T lymphocyte count. d The RIG-I expression decreased significantly after therapy. The number of lymphocytes and T lymphocyte were increased at the 3-month follow-up period