Table 2 Characteristics of patients with “seronegative” and “seropositive” early arthritis at 3 years (n = 617)
Seronegative (n = 242) | Seropositive (n = 375) | P value* | |
|---|---|---|---|
TJC, mean (SD) | 3 (5.3) | 2.9 (5.3) | 0.900 |
SJC, mean (SD) | 1 (2) | 1.5 (2.7) | 0.034 |
ESR, mm/h, mean (SD) | 12.4 (10.4) | 16.6 (14.7) | < 0.001 |
CRP, mg/L mean (SD) | 6 (11) | 7.3 (11.6) | 0.025 |
DAS28, mean (SD) | 2.8 (1.3) | 2.9 (1.4) | 0.211 |
DAS28 < 2.6, n (%) | 115 (49.4%) | 170 (47.4%) | 0.634 |
HAQ-DI, mean (SD) | 0.5 (0.6) | 0.5 (0.6) | 0.980 |
mTSS, mean (SD) | 10.7 (12.1) | 16.3 (15.8) | < 0.001 |
Δ mTSS versus baseline, mean (SD) | 5.8 (7.9) | 10.4 (11.3) | < 0.001 |
2010 ACR/EULAR criteria (≥ 6/7 points), n (%) | 189/233 (81.1%) | 369/371 (99.4%) | < 0.001 |
Based on score ≥ 6 | 166/229 (72.5%) | 366/371 (98.7%) | < 0.001 |
Typical RA erosion | 71/242 (29.3%) | 235/375 (62.7%) | < 0.001 |
cs and b DMARDs, n (%) | 134 (55.6%) | 302 (80.8%) | < 0.001 |
cs DMARDs, n (%) | 133 (55.2%) | 290 (77.5%) | < 0.001 |
b DMARDs, n (%) | 10 (4.2%) | 67 (17.9%) | < 0.001 |
Corticosteroids, n (%) | 59 (24.5%) | 130 (34.8%) | 0.007 |