|
Metformin users (mean, SE)1
|
Non-users (mean, SE)1
|
Difference (mean, 95% CI)1
|
P
1
|
Metformin users (mean, SE)2
|
Non-users (mean, SE)2
|
Difference (mean, 95% CI)2
|
P
2
|
---|
Medial cartilage volume loss (%)
|
0.83 (0.34)
|
1.55 (0.07)
|
− 0.72 (− 1.42, − 0.02)
|
0.04
|
0.71 (0.35)
|
1.57 (0.07)
|
− 0.86 (− 1.58, − 0.15)
|
0.02
|
Lateral cartilage volume loss (%)
|
0.98 (0.29)
|
1.22 (0.06)
|
− 0.24 (− 0.85, 0.36)
|
0.43
|
1.03 (0.28)
|
1.24 (0.06)
|
− 0.20 (− 0.79, 0.38)
|
0.49
|
- SE standard error, CI confidence interval
- 1Adjusted for age, gender, body mass index, Kellgren-Lawrence grade, WOMAC pain score, and diabetes
- 2Adjusted for age, gender, body mass index, Kellgren-Lawrence grade, WOMAC pain score, diabetes, and weight change over 4 years