Table 1 Demographic and clinical features associated with peripheral arthritis in patients with recent onset axial spondyloarthritis
Baseline (M0) | Any arthritis N = 255 (%) | No arthritis N = 453 (%) | OR (95%CI) Univariate analysis | p value* | OR (95%CI) Multivariate analysis | p value** |
|---|---|---|---|---|---|---|
Female gender | 147 (57.6) | 234 (51.7) | 1.27 (0.93–1.74) | 0.125 | ||
Age ≥ 33 years old (median age) | 148 (58.0) | 212 (46.8) | 1.57 (1.15–2.14) | 0.004 | 1.60 (1.12–2.27) | 0.009 |
Non-Caucasian ethnicity | 34 (13.3) | 40 (8.8) | 1.60 (0.98–2.58) | 0.062 | ||
White collar profession | 210 (82.4) | 387 (85.4) | 0.80 (0.53–1.21) | 0.280 | ||
High level of education (Univ.) | 143 (56.1) | 275 (60.7) | 0.83 (0.61–1.13) | 0.230 | ||
Non-smokers | 179 (70.2) | 272 (60.0) | 1.57 (1.13–2.17) | 0.007 | 1.58 (1.10–2.27) | 0.014 |
Alcohol exposure | 43 (16.9) | 61 (13.5) | 1.30 (0.85–1.99) | 0.221 | ||
HLAB27 negativity | 125 (49.0) | 173 (38.2) | 1.56 (1.14–2.12) | 0.005 | 1.47 (1.04–2.08) | 0.029 |
Absence of MRI-SIJ inflammatory lesionsa | 177 (69.4) | 296 (65.3) | 1.20 (0.87–1.67) | 0.270 | ||
No modified NY criteriaa | 223 (87.5) | 373 (82.3) | 1.49 (0.96–2.33) | 0.075 | ||
CRP ≥ 6 mg/dl | 90 (35.3) | 105 (23.2) | 1.81 (1.29–2.53) | 0.001 | 1.99 (1.35–2.92) | < 0.001 |
Psoriasis | 52 (20.4) | 66 (14.6) | 1.50 (1.01–2.24) | 0.047 | ||
No history of uveitis | 238 (93.3) | 405 (89.4) | 1.66 (0.93–2.95) | 0.085 | 2.03 (1.07–3.84) | 0.030 |
IBD (Crohn or ulcerative colitis) | 10 (3.9) | 25 (5.5) | 0.70 (0.33–1.50) | 0.349 | ||
Dactylitis | 76 (29.8) | 21 (4.6) | 8.73 (5.23–14.60) | < 0.001 | 8.50 (4.96–14.60) | < 0.001 |
Enthesitis (any location) | 174 (68.2) | 222 (49.0) | 2.23 (1.62–3.08) | < 0.001 | 2.00 (1.41–2.84) | < 0.001 |
Family history of SpA | 102 (40.0) | 191 (42.2) | 9.91 (0.67–1.25) | 0.575 |