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Table 1 Demographic and clinical features associated with peripheral arthritis in patients with recent onset axial spondyloarthritis

From: Evaluation of concomitant peripheral arthritis in patients with recent onset axial spondyloarthritis: 5-year results from the DESIR cohort

Baseline (M0) Any arthritis
N = 255 (%)
No arthritis
N = 453 (%)
OR (95%CI)
Univariate analysis
p value* OR (95%CI)
Multivariate analysis
p value**
Female gender 147 (57.6) 234 (51.7) 1.27 (0.93–1.74) 0.125   
Age ≥ 33 years old (median age) 148 (58.0) 212 (46.8) 1.57 (1.15–2.14) 0.004 1.60 (1.12–2.27) 0.009
Non-Caucasian ethnicity 34 (13.3) 40 (8.8) 1.60 (0.98–2.58) 0.062   
White collar profession 210 (82.4) 387 (85.4) 0.80 (0.53–1.21) 0.280   
High level of education (Univ.) 143 (56.1) 275 (60.7) 0.83 (0.61–1.13) 0.230   
Non-smokers 179 (70.2) 272 (60.0) 1.57 (1.13–2.17) 0.007 1.58 (1.10–2.27) 0.014
Alcohol exposure 43 (16.9) 61 (13.5) 1.30 (0.85–1.99) 0.221   
HLAB27 negativity 125 (49.0) 173 (38.2) 1.56 (1.14–2.12) 0.005 1.47 (1.04–2.08) 0.029
Absence of MRI-SIJ inflammatory lesionsa 177 (69.4) 296 (65.3) 1.20 (0.87–1.67) 0.270   
No modified NY criteriaa 223 (87.5) 373 (82.3) 1.49 (0.96–2.33) 0.075   
CRP ≥ 6 mg/dl 90 (35.3) 105 (23.2) 1.81 (1.29–2.53) 0.001 1.99 (1.35–2.92) < 0.001
Psoriasis 52 (20.4) 66 (14.6) 1.50 (1.01–2.24) 0.047   
No history of uveitis 238 (93.3) 405 (89.4) 1.66 (0.93–2.95) 0.085 2.03 (1.07–3.84) 0.030
IBD (Crohn or ulcerative colitis) 10 (3.9) 25 (5.5) 0.70 (0.33–1.50) 0.349   
Dactylitis 76 (29.8) 21 (4.6) 8.73 (5.23–14.60) < 0.001 8.50 (4.96–14.60) < 0.001
Enthesitis (any location) 174 (68.2) 222 (49.0) 2.23 (1.62–3.08) < 0.001 2.00 (1.41–2.84) < 0.001
Family history of SpA 102 (40.0) 191 (42.2) 9.91 (0.67–1.25) 0.575   
  1. All results are presented as n (%). Percentages indicate number of patients with the covariate from the total number of patients in each category
  2. mNY modified New York criteria, MRI-SIJ magnetic resonance imaging on sacroiliac joints, Univ. university
  3. *p value for the univariate analysis
  4. **p value for the multivariate analysis
  5. amNY criteria and MRI inflammatory lesions according to the local investigator