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Table 4 Association between NAR expression and neutrophil count

From: Type I interferon in patients with systemic autoimmune rheumatic disease is associated with haematological abnormalities and specific autoantibody profiles

 

Beta coefficient (95% CI)

Univariate model

Adjusted model 1†

Adjusted model 2†

Adjusted model 3†

TLR3

−0.113 (−0.206, −0.019)*

−0.121 (−0.212, −0.030)*

− 0.116 (− 0.203, − 0.29)*

−0.107 (− 0.194, − 0.022)*

TLR9

0.161 (0.072, 0.250)*

0.138 (0.048, 0.229)*

0.102 (0.011, 0.193)*

0.095 (0.006, 0.184)*

MB21D1

0.151 (0.065, 0.237)*

0.126 (0.039, 0.213)*

0.096 (0.008, 0.184)*

0.100 (0.015, 0.186)*

  1. Linear regression models of log-normalised neutrophil counts
  2. †Model 1: adjusted for age, gender, ethnicity (Caucasian vs non-Caucasian) and clinical diagnosis
  3. Model 2: as above plus adjusted for prednisolone, anti-malarial and immunosuppressant use
  4. Model 3: as above plus adjustment for ISG score
  5. *p < 0.05
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Arthritis Research & Therapy

ISSN: 1478-6362

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