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Table 5 Baseline predictive factors of CS less than 7.5 mg/day analyzed by multivariate analysis

From: Comparative study of corticosteroid monotherapy, and TNF inhibitors with or without corticosteroid in patients with refractory entero-Behcet’s disease

Variables

Univariate logistic regression

Multiple logistic regression

Wald

P

OR (95%CI)

Wald

P

OR (95%CI)

Male, n (%)

0.9232

0.3365

0.53 (0.15–1.92)

   

Age (years)

5.1680

0.0230

1.07 (1.01–1.14)

2.32

0.1135

1.06 (0.98–1.13)

Disease duration (entero-BD, months)

0.0186

0.8914

1.00 (0.99–1.01)

   

Multiple ulceration, n (%)

3.6556

0.1559

0.26 (0.06–1.03)

   

History of relapse, n (%)

0.3876

0.5336

0.53 (0.43–5.05)

   

History of perforation, n (%)

0

1.0000

1.00 (0.18–5.63)

   

History of surgery, n (%)

0.1704

0.6797

0.71 (0.14–3.64)

   

Concomitant CS dose (mg/day)

1.0678

0.3014

0.98 (0.95–1.02)

   

Concomitant colchicine use, n (%)

2.4121

0.1139

2.75 (0.767–9.86)

   

Concomitant drugs use, n (%) (MTX, MS/SSZ, AZ)

1.2318

0.2556

2.40 (0.51–11.3)

   

Concomitant MTX use, n (%)

11.811

0.0006

15.0 (3.20–70.4)

2.32

0.5228

2.38 (0.16–34.2)

TNF-i use, n (%)

15.033

< 0.0001

25.5 (4.96–131.1)

3.11

0.0778

10.8 (0.77–153.0)

DAIBD

2.3752

0.1233

0.98 (0.97–1.00)

   
  1. Model χ2 test P < 0.0001. BD Behcet’s disease, CS corticosteroid, col colchicine, MS mesalazine, SSZ sulfasalazine, MTX methotrexate, AZ azathioprine, TNF-i TNF inhibitors, DAIBD disease activity index for intestinal Behcet’s disease